Description
General Dosing Administration: Oxaliplatin lyophilized powder should be reconstituted and diluted prior to IV infusion.
Oxaliplatin is administered by intravenous infusion.
Dosage given should be adjusted according to tolerability.
If severe/life-threatening diarrhea, neurotoxicity or hematological toxicity occurs, a dose adjustment may be required.
Antiemetics (5-HT3 blockers with or without dexamethasone) should be given during pre- and post-therapy with oxaliplatin since oxaliplatin is highly emetogenic.
Oxaliplatin should always be administered before fluoropyrimidines (i.e., 5-FU).
Oxaliplatin administration does not require prehydration.
Use only the recommended diluents in preparing the solution. (See Incompatibilities under Cautions for Usage).
