Description

Contents: Carboplatin.

Description: Each mL contains: Carboplatin Ph. Eur. 10 mg.

Action: Pharmacotherapeutic group: Antineoplastic agents, Platinum compounds. ATC code: LO1X A02.

Pharmacology: Pharmacodynamics: Carboplatin is an antineoplastic agent. Its activity has been demonstrated against several murine and human cell lines.
Carboplatin exhibited comparable activity to cisplatin against a wide range of tumors regardless of implant site.

Alkaline elution techniques and DNA binding studies have demonstrated the qualitatively similar modes of action of Carboplatin and cisplatin. Carboplatin, like cisplatin, induces changes in the superhelical conformation of DNA, which is consistent with a “DNA shortening effect”.

Pediatric patients: safety and efficacy in children have not been established.